Dec 02, 2024  
Catalog 2019-2020 
    
Catalog 2019-2020 [ARCHIVED CATALOG]

BIOL 226 Principles of Molecular Diagnostics

5 credits
This course provides an overview of fundamental principles of molecular diagnostics and explores the use of molecular techniques in disease diagnostics. Topics to be covered include: DNA replication, isolation, transcription, gene expression and regulation, recombinant DNA and RNA techniques, and DNA amplification such as QPCR and hybridization techniques used in infectious disease diagnosis. Course includes laboratory.

Prerequisites: BIOL& 160  or BIOL& 211  

Course Outcomes
Upon successful completion of this course students will be able to:

  • Apply knowledge of cellular structure, especially DNA and RNA, to molecular procedures
  • Explain the basic principles of modern genetics as they apply to disease transmission
  • Evaluate methods for analysis and characterization of nucleic acids and proteins
  • Analyze chromosomal structure and mutations 
  • Apply methods to detect mutations
  • Explain nucleic acid extraction, resolution, and detection
  • Analyze the most commonly utilized molecular diagnostic testing protocols
  • Analyze techniques used in a molecular diagnostics lab to detect: DNA polymorphisms, microorganisms, inherited diseases, neoplastic diseases, and DNA-based tissue typing

Total Hours: 70 Lecture Hours: 30 Lab or Clinical Hours: 40